Introduction: Aesthetic procedures of skin regeneration and treatments are finding more and more use in daily practice. Today’s trend leans towards non-invasive procedures compared to the number of these procedures performed in the previous years. The correct application of hyaluronic acid filler by trained doctors is accompanied by a small number or no complications at all. Purpose of this paper: To emphasize the importance of qualification in hyaluronic acid (Filler) injection procedures. To acknowledge and understand the possible complications and re-emphasize the ways of managing them after the application of hyaluronic acid. Materials and Methods: Patients treated with hyaluronic acid injections (Fillers) who developed complications after the procedure. The selected sample in this referral bases on the material and experience from our clinical cases encountered in the daily practice of 15 years. Results: Complications after hyaluronic acid injections are classified as immediate complications and delayed complications. The number of complications immediately after the procedure is larger compared to the number of complications that develop later and includes pain, edema, discomfort, hematoma, infections, nodules, vascular-necrosis compression, blindness. The number of delayed complications is smaller and includes infections, granulomas, filler migration. Conclusions: Every injection procedure (Filler) contains the possibility of developing complications. Therefore, we can’t say that an ideal filler does exist. Hyaluronic acid injection procedures are safe and effective procedures if applied by trained medical personnel. Having strong knowledge of anatomy and acquiring updated information on this sub-specialty, especially on the treatment of complications, is a necessity for the medical staff that performs these procedures. Aesthetic medicine is the bridge between medicine and art and should be entrusted to experts.
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