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In this issue, we are pleased to share interesting data and hypotheses generated in the international scientific community in 2021.

Pierfrancesco Morganti and co-workers report on the Chinese-Italian cooperation in the strategic choices of the International Society of Cosmetic Dermatology. The worldwide increase of greenhouse gas (GHG) emissions and the numerous deaths seen during the COVID-19 pandemic, caused by an unknown virus and pollution, has highlighted the States’ inability and unwillingness to protect its citizens. Therefore, there is an urgent need to de-escalate the negative effects of these emissions by producing and using nature-oriented ingredients that are plastic-free and sustainable, improving public healthcare structures. The agreement signed between the dermatological department of the First Hospital of the China Medical University of Shenyang and the engineering department of La Sapienza University in Rome, Italy, aims at this. According to this interesting report, the common project between the China Medical University and the Academy of History of Healthcare Art in Rome, aims to obtain better wealth for Chinese and Italian citizens.

Pier Antonio Bacci and colleagues report on the vascularizing action of the compressive microvibration endospheres. Compressive Microvibration Endosphères uses 55 rotating microspheres to create particular vibratory stimuli on the energy points and the tissues to obtain optimal functional responses to vascularize, drain and regenerate, finally to reduce the pain of the tissues with fibroedema and lymphatic stasis. In 2007, the preliminary studies of this method were presented; since then and up to now, there have been interesting studies and clinical experiences that show a constant and typical vascularizing action and thermal tissue increase that opens up interesting reflections about the relationship between microvibration and vascularization. In the light of current scientific knowledge, the retrospective study is the aim of this work published in this issue.

Caterina Dianzani and colleagues report, in a very interesting letter to the editor, on a new

fluorescein product containing topical 2% fluorescein solution combined with extracts of Melaleuca alternifolia and Uncaria tomentosa for optimizing the wound healing process after skin surgery.

Carlo Braga and co-workers report on the efficacy and safety of a new medical device in

regulating abnormal sweating dealing with hyperhidrosis and bromhidrosis; this is an interesting report showing new data of great interest.

Pier Antonio Bacci and co-workers contribute to this issue with a paper on thermographic and clinical data (TCD Code) in evaluating cellulite treatment by Endosphères Therapy. According to this report, a significant improvement of cellulite is reachable by using specific micro-vibrations associated with micro-compression.

A retrospective study of Domenico D’Angelo and co-workers shows in this paper the application of a successful new procedure for the treatment of lipolymphedema and the alteration of the interstitial matrix in the common cellulite.

We congratulate the Authors on their excellent publications in this issue, and we hope that the scientific community and the single affected subjects will benefit from such interesting reports.

Torello Lotti MD, FRCP (Edinburgh)

Editor in Chief

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